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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recommended positive controls: A431, A431 membrane extract.
Predicted reactivity: Mouse (90%), Rat (91%), Rhesus Monkey (100%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AT15655p; CG1134-PA; CG1134-PB; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; Growth inhibition and death E3 ligase; Mitochondrial E3 ubiquitin protein ligase 1; mitochondrial E3 ubiquitin protein ligase 1 homologue; Mitochondrial E3 ubiquitin protein transferase 1; Mitochondrial ubiquitin ligase activator of NFKB 1; Mitochondrial-anchored protein ligase; Mul1-PA; Mul1-PB; Protein Hades; Putative NF-kappa-B-activating protein 266; RING finger protein 218; RING-type E3 ubiquitin transferase NFKB 1; RP11-401M16.2
基因别名: C1orf166; CG1134; Dmel\CG1134; Dmel_CG1134; GIDE; MAPL; MUL1; MULAN; RNF218
UniProt ID: (Fruit fly) Q9VZJ9
Entrez Gene ID: (Fruit fly) 38472