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Invitrogen
Caspase 4 Polyclonal Antibody
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FIGURE: 1 / 8
Caspase 4 Antibody (PA5-29788) in IHC (P)
Caspase 4 Polyclonal Antibody detects CASP4 protein at cytosol on SAS xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SAS xenograft. Caspase 4 Polyclonal Antibody (Product # PA5-29788) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-29788
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Caspase 4. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.89 mg/mL
Amount
89 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: H1299, K562, THP-1, HL-60, myc-tagged human caspas4-transfected 293T cells.
Predicted reactivity: Rhesus Monkey (96%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CASP-1; CASP-4; Caspase-1; caspase-1/caspase-4 hybrid; Caspase-4; ICE; ICE and Ced-3 homolog 2; ICE(rel)-II; ICH-2; IL-1 beta-converting enzyme; IL-1BC; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; member of caspase family; Mih1; p45; Protease TX
Gene Aliases: CASP1; CASP4; ICH2; IL1BC
UniProt ID: (Dog) Q9MZV7
Entrez Gene ID: (Dog) 403724
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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