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Invitrogen
ME1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-40600
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human ME1 (aa 36-85).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: QQLNIHGLLP PSFNSQEIQV LRVVKNFEHL NSDFDRYLLL MDLQDRNEKL
Sequence homology: Cow: 92%; Dog: 85%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 91%; Rabbit: 100%; Rat: 100%; Sheep: 92%
靶标信息
ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Malic enzyme 1; malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; NADP-dependent malic enzyme; NADP-ME; pyruvic-malic carboxylase; unnamed protein product
基因别名: HUMNDME; ME1; MES
Entrez Gene ID: (Human) 4199
magnesium ion binding
malic enzyme activity
malate dehydrogenase (decarboxylating) (NADP+) activity
protein binding
oxaloacetate decarboxylase activity
electron carrier activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
manganese ion binding
identical protein binding
ADP binding
NADP binding
NAD binding
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