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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptide sequence: GSALDDAVNP LHENGDDSLS PRLGWPLDQD RSKGDSDPKP GSPKVKEYVS
Sequence homology: Cow: 92%; Guinea Pig: 83%; Horse: 83%; Human: 100%; Pig: 92%; Rabbit: 92%
Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。