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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total CMTM1 protein.
Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules. As a member of the CKLFSF family of proteins, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1 (Chemokine-like factor superfamily member 1), is a 169 amino acid multi-pass membrane protein that is highly expressed in testis, therefore probably playing a role in spermatogenesis or testicular development. CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3 and CMTM4. There are at least sixteen isoforms of CMTM1 that are produced as a result of alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chemokine-like factor super family 1; chemokine-like factor superfamily 1; chemokine-like factor superfamily member 1; chemokine-like factor-like protein CKLFH1; CKLFSF1_v1; CKLFSF1_v10; CKLFSF1_v11; CKLFSF1_v12; CKLFSF1_v13; CKLFSF1_v14; CKLFSF1_v15; CKLFSF1_v16; CKLFSF1_v19; CKLFSF1_v2; CKLFSF1_v20; CKLFSF1_v21; CKLFSF1_v22; CKLFSF1_v23; CKLFSF1_v3; CKLFSF1_v4; CKLFSF1_v5; CKLFSF1_v6; CKLFSF1_v7; CKLFSF1_v8; CKLFSF1_v9; cytokine; from transcript variant 24
Gene Aliases: CKLFH; CKLFH1; CKLFSF1
UniProt ID: (Human) Q8IZ96
Entrez Gene ID: (Human) 113540
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