Invitrogen

CATSPER3 Polyclonal Antibody

Name: CATSPER3 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-50374
Availability: InStock

查看其他2个CATSPER3抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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CATSPER3 Antibody (PA5-50374) in WB

Western Blot analysis of CATSPER3 was performed using Mouse testis tissue lysates. The membrane was probed using CATSPER3 Polyclonal Antibody (Product # PA5-50374) 1:350 dilution. Secondary antibody dilution: 1:8,000. Exposure time: 2 minutes.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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产品信息

PA5-50374

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Fusion protein corresponding to a region derived from internal residues of human cation channel, sperm associated 3

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.3 mg/mL

130 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 40% glycerol

内含物

0.05% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2635827

产品详细信息

The antibody detects endogenous levels of total CATSPER3 protein.

靶标信息

CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

仅用于科研。不用于诊断过程。未经明确授权不得转售。