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Invitrogen
CYP26A1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50944
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from the Internal region of human CYP26A1 (aa 251-300).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
CYP26A1 Polyclonal Antibody detects endogenous levels of CYP26A1 protein.
Target Information
CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CYP26A1; cytochrome P450 retinoic acid-inactivating 1; cytochrome P450, 26, retinoic acid; cytochrome P450, 26, retinoic acid A1; cytochrome P450, family 26, subfamily A, polypeptide 1; cytochrome P450, subfamily XXVIA, polypeptide 1; cytochrome P450RAI; hP450RAI; P450, retinoic acid-inactivating, 1; retinoic acid 4-hydroxylase; retinoic acid hydrolase; retinoic acid hydroxylase; retinoic acid-metabolizing cytochrome; tuftelin-interacting protein 24 TIP-24; unnamed protein product
Gene Aliases: CP26; CYP26; P450RA; P450RAI; P450RAI1; RAH
UniProt ID: (Human) O43174, (Mouse) O55127
Entrez Gene ID: (Human) 1592, (Mouse) 13082, (Rat) 154985
retinoic acid binding
monooxygenase activity
iron ion binding
retinoic acid 4-hydroxylase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
all-trans retinoic acid 4-hydrolase activity
all-trans retinoic acid 18-hydroxylase activity
xenobiotic metabolic process
central nervous system development
anterior/posterior pattern specification
neural crest cell development
retinoic acid catabolic process
retinoic acid metabolic process
retinoic acid receptor signaling pathway
cellular response to retinoic acid
kidney development
response to retinoic acid
response to vitamin A
vitamin metabolic process
negative regulation of retinoic acid receptor signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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