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Invitrogen
GPR56 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50979
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from the Internal region of human GPR56.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
GPR56 Polyclonal Antibody detects endogenous levels of GPR56 protein.
Target Information
GPR56 is a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7-transmembrane protein with no EGF-like N-terminal domains-1; adhesion G-protein coupled receptor G1; CYT28; DKFZp781L1398; G protein-coupled receptor 56; G-protein coupled receptor 56; secretin receptor; serpentine receptor cyt28; seven transmembrane receptor; secretin family; SLR32; testicular tissue protein Li 77; unnamed protein product
Gene Aliases: BFPP; BPPR; CDCBM14B; CDCBM15A; Cyt28; GPR56; TM7LN4; TM7XN1
UniProt ID: (Human) Q9Y653, (Mouse) Q8K209
Entrez Gene ID: (Human) 9289, (Rat) 260326, (Mouse) 14766
angiogenesis
cell adhesion
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
Rho protein signal transduction
brain development
negative regulation of cell proliferation
positive regulation of signal transduction
cell migration
cerebral cortex regionalization
cerebral cortex radial glia guided migration
layer formation in cerebral cortex
positive regulation of Rho protein signal transduction
tube development
regulation of cell proliferation
positive regulation of cell adhesion
anatomical structure formation involved in morphogenesis
hematopoietic stem cell homeostasis
oligodendrocyte progenitor proliferation
seminiferous tubule development
regulation of platelet aggregation
negative regulation of ferroptosis
Rho-activating G protein-coupled receptor signaling pathway
positive regulation of vascular endothelial growth factor signaling pathway
regulation of synapse pruning
positive regulation of neural precursor cell proliferation
negative regulation of neuron migration
cell-cell signaling
synapse pruning
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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