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Invitrogen
ATP4B Polyclonal Antibody
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FIGURE: 1 / 1
ATP4B Antibody (PA5-78839) in WB
Western blot analysis of ATP4B in rat stomach extract (lane 1), mouse stomach extract (lane 2) and SGC7901 whole cell lysate (lane 3). Sample was incubated with ATP4B polyclonal antibody (Product # PA5-78839) at a dilution of 0.5 µg/mL. Signal development was performed using a chemiluminescence (ECL) kit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-78839
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ATP4B (1-28aa MAALQEKKTCGQRMEEFQRYCWNPDTGQ).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat stomach tissue, mouse stomach tissue, SGC7901 whole cell.
Target Information
The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subunit. Like the ubiquitous sodium/potassium ATPase, the hydrogen/potassium ATPase consists of a large transmembrane catalytic subunit, termed the alpha- subunit which contains sites for ATP binding and phosphorylation, and an associated smaller glycoprotein, termed the beta-subunit which may play a role in maintaining the structural and functional integrity of the complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase H+/K+ transporting beta subunit; ATPase H+K+-transporting beta / (gastric HK-ATPase beta subunit) defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide, gastric specific; gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+ ATPase beta subunit; gastric hydrogen-potassium ATPase, beta; H+,K+-ATPase; H+/K+ ATPase beta; H+/K+-ATPase beta; H,K-ATPase-Beta; potassium-transporting ATPase beta chain; proton pump beta chain; unnamed protein product
Gene Aliases: ATP6B; S76401S1
UniProt ID: (Human) P51164, (Rat) P18598, (Mouse) P50992
Entrez Gene ID: (Human) 496, (Rat) 24217, (Mouse) 11945
potassium ion transport
sodium ion transport
cellular sodium ion homeostasis
cellular potassium ion homeostasis
response to lipopolysaccharide
sodium ion export from cell
pH reduction
hydrogen ion transmembrane transport
potassium ion import across plasma membrane
potassium ion transmembrane transport
glycoprotein biosynthetic process
regulation of proton transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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