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Invitrogen
BCAR3 Polyclonal Antibody
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BCAR3 Antibody (PA5-78858) in IHC (P)
Immunohistochemistry analysis of BCAR3 on paraffin-embedded mouse lymphaden tissue. Sample was incubated with BCAR3 polyclonal antibody (Product# PA5-78858) with a dilution of 1 µg/mL, and developed by Streptavidin-Biotin-Complex (SABC) with DAB chromogen method.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-78858
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human BCAR3 (791-825aa KGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HEPG2 whole cell. IHC: mouse lymphaden tissue, rat spleen tissue, human tonsil tissue.
靶标信息
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BCAR3 adapter protein, NSP family member; Breast cancer anti-estrogen resistance protein 3; Breast cancer anti-estrogen resistance protein 3 homolog; KIAA0554; Novel SH2-containing protein 2; OTTHUMP00000011961; p130Cas-binding protein AND-34; SH2 domain-containing protein 3B
基因别名: AI131758; AND-34; And34; BCAR3; NSP2; SH2D3B; UNQ271/PRO308
UniProt ID: (Mouse) Q9QZK2, (Rat) D3ZAZ5
Entrez Gene ID: (Mouse) 29815, (Rat) 310838
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