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Invitrogen
CXCL10 Polyclonal Antibody
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FIGURE: 1 / 2
CXCL10 Antibody (PA5-79104) in IHC (P)
Immunohistochemistry analysis of CXCL10 (IP-10) in paraffin-embedded section of mouse spleen tissue. Samples were incubated with CXCL10 (IP-10) polyclonal antibody (Product # PA5-79104) using a dilution of 2 μg/mL overnight at 4°C followed by Peroxidase Conjugated Goat Anti-rabbit IgG incubated for 30 minutes at 37°C. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval so... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79104
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived mouse IP10 recombinant protein (Position: I22-P98).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - IHC: mouse spleen tissue.
Target Information
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 10 kDa interferon gamma-induced protein; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; CXC; CXC motif chemokine; CXCL; gamma-IP10; H-IP-10; interferon activated gene 10; interferon-gamma induced protein CRG-2; M-IP-10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small-inducible cytokine B10; unnamed protein product
Gene Aliases: C7; CRG-2; gIP-10; Ifi10; INP10; IP-10; IP10; mob-1; Scyb10
UniProt ID: (Mouse) P17515
Entrez Gene ID: (Mouse) 15945
positive regulation of leukocyte chemotaxis
chemotaxis
defense response
inflammatory response
immune response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
response to bacterium
T cell chemotaxis
regulation of T cell chemotaxis
negative regulation of angiogenesis
positive regulation of cell migration
neutrophil chemotaxis
killing of cells of other organism
endothelial cell activation
regulation of cell proliferation
regulation of apoptotic process
negative regulation of myoblast differentiation
positive chemotaxis
positive regulation of release of sequestered calcium ion into cytosol
defense response to virus
antimicrobial humoral immune response mediated by antimicrobial peptide
chemokine-mediated signaling pathway
cellular response to lipopolysaccharide
positive regulation of monocyte chemotaxis
cellular response to interleukin-17
cellular response to virus
antiviral innate immune response
regulation of endothelial tube morphogenesis
negative regulation of myoblast fusion
positive regulation of T cell migration
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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