Invitrogen

Aminoacylase Polyclonal Antibody

Name: Aminoacylase Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-81310
Availability: InStock

1 篇参考文献

查看其他23个Aminoacylase抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (4)

Aminoacylase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 4

Aminoacylase Antibody (PA5-81310) in IHC (P)

Immunohistochemical staining of mouse Aminoacylase in mouse kidney with Aminoacylase Polyclonal Antibody (Product # PA5-81310, 1:5,000, formalin-fixed paraffin embedded sections).

Aminoacylase Antibody in Western Blot (WB)

Aminoacylase Antibody in Immunoprecipitation (IP)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image Aminoacylase Polyclonal Antibody

产品信息

PA5-81310

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:2,500-1:10,000

免疫组化（冰冻） (IHC (F))

查看1篇已发表文章 1篇已发表文章

酶联免疫吸附实验 (ELISA)

1:25,000-1:50,000

免疫沉淀 (IP)

0.2-1 µL/mg of lysate

产品规格

种属反应

Mouse

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Mouse Aminoacylase-1/ACY1 Protein (Met1-Ser408)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2788527

产品详细信息

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Mouse Aminoacylase-1/ACY1.

靶标信息

ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21. 1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene. A related pseudogene has been identified on chromosome 18.

仅用于科研。不用于诊断过程。未经明确授权不得转售。