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Invitrogen
E2F8 Polyclonal Antibody
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E2F8 Antibody (PA5-88117) in WB
Western blot analysis of E2F8 in extracts of various cell lines. Samples were incubated with E2F8 Polyclonal antibody (Product # PA5-88117) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-88117
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 788-867 of human E2F8 (NP_0789562)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
4.3 mg/mL
规格
430 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PVPGQSQPNG QSVAVTGAQQ PVPVTPKGSQ LVAESFFRTP GGPTKPTSSS CMDFEGANKT SLGTLFVPQR KLEVSTEDVH
Positive Samples: SW480, Mouse testis; Cellular Location: Nucleus
靶标信息
E2F transcription factors, such as E2F8, are essential for orchestrating expression of genes required for cell cycle progression and proliferation (Christensen et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E2F 8; E2f family member 8; E2F-8; FLJ23311; Transcription factor E2F8
基因别名: 4432406C08Rik; AA410048; E2f8
UniProt ID: (Mouse) Q58FA4
Entrez Gene ID: (Mouse) 108961
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
identical protein binding
protein homodimerization activity
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell cycle
cell proliferation
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
cell cycle comprising mitosis without cytokinesis
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
