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Invitrogen
AKAP7 Polyclonal Antibody
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FIGURE: 1 / 1
AKAP7 Antibody (PA5-88238) in WB
Western blot analysis of AKAP7 in extracts of various cell lines. Samples were incubated with AKAP7 Polyclonal antibody (Product # PA5-88238) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-88238
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
3.28 mg/mL
Amount
328 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MGQLCCFPFS RDEGKISEKN GGEPDDAELV RLSKRLVENA VLKAVQQYLE ETQNKNKPGE GSSVKTEAAD QNGNDNENNR K; Positive Samples: Mouse brain, Rat brain; Cellular Location: Apical cell membrane, Lateral cell membrane, Lipid-anchor, Lipid-anchor
Target Information
This gene encodes a member of the A-kinase anchoring protein family, a group of functionally related proteins that bind to a regulatory subunit of cAMP-dependent protein kinase A and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-kinase anchor protein 18; A-kinase anchor protein 18 {ECO:0000250|UniProtKB:F8VQ58}; A-kinase anchor protein 7; A-kinase anchor protein 7 isoform alpha; A-kinase anchor protein 7 isoform gamma; A-kinase anchor protein 7 isoforms delta and gamma; A-kinase anchor protein 9 kDa; A-kinase anchoring protein 18 ,isoform delta; AKAP 9; AKAP-18; AKAP-18 {ECO:0000250|UniProtKB:F8VQ58}; AKAP-7 isoform alpha; AKAP-7 isoform gamma; AKAP-7 isoforms delta and gamma; akap7; akap7 {ECO:0000312|RGD:1303071}; PRKA7 isoform alpha; PRKA7 isoform gamma; PRKA7 isoforms delta and gamma; protein kinase A anchoring protein 7; Protein kinase A-anchoring protein 7 isoform alpha; Protein kinase A-anchoring protein 7 isoform gamma; Protein kinase A-anchoring protein 7 isoforms delta and gamma
Gene Aliases: 6430401D08; AI662165; AKAP-18; AKAP15; Akap18; AKAP18d; Akap7; BB170514
UniProt ID: (Mouse) O55074, (Rat) Q6JP77
Entrez Gene ID: (Mouse) 432442, (Rat) 361458
transmembrane receptor protein serine/threonine kinase signaling pathway
protein localization
regulation of protein kinase A signaling
regulation of membrane repolarization
cellular response to cAMP
positive regulation of potassium ion transmembrane transport
positive regulation of delayed rectifier potassium channel activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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