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Invitrogen
UBE1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-88493
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human UBA1 (NP_6950121)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.57 mg/mL
规格
57 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KISFKSLVAS LAEPDFVVTD FAKFSRPAQL HIGFQALHQF CAQHGRPPRP RNEEDAAELV ALAQAVNARA LPAVQQNNLD EDLIRKLAYV AAGDLAPINA FIGGLAAQEV MKACSGKFMP IMQWLYFDAL ECLPEDKEVL TEDKCLQRQN RYDGQVAVFG SDLQEKLGKQ KYFLVGAGAI GCELLKNFAM IGLGCGEGGE IIVTDMDTIE KSNLNRQFLF RPWDVTKLKS DTAAAAVRQM NPHIRVTSHQ NRVGPDTERI YDDDFFQNLD GVANALDNVD ARMYMDRRCV YYRKPLLESG T; Positive Samples: U-251MG, Rat spleen; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, Nucleus
靶标信息
UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11. 23. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A1S9 protein; uba1 {ECO:0000312|EMBL:AAH85791.1, ECO:0000312|RGD:1359327}; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1 X; ubiquitin-activating enzyme E1 {ECO:0000250|UniProtKB:Q02053}; ubiquitin-activating enzyme E1, Chr X; Ubiquitin-like modifier-activating enzyme 1; Ubiquitin-like modifier-activating enzyme 1 X; ubiquitin-like modifier-activating enzyme 1 {ECO:0000250|UniProtKB:Q02053}
基因别名: A1S9; Sbx; Uba1; Ube-1; Ube1; Ube1ax; Ube1x
UniProt ID: (Mouse) Q02053, (Rat) Q5U300
Entrez Gene ID: (Mouse) 22201, (Rat) 314432
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