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Invitrogen
TRH Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-89851
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.58 mg/mL
Amount
58 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: U-87MG, BXPC-3, A-549, DU145, Mouse brain, Rat testis
Immunogen sequence: WLAYAVPKRQ HPGRRLADPK AQRSWEEEEE EEEREEDLMP EKRQHPGKRA LGGPCGPQGA YGQAGLLLGL LDDLSRSQGA EEKRQHPGRR AAWVREPLEE
Target Information
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pre-pro thyrotropin releasing hormone; pro-thyrotropin-releasing hormone; prothyroliberin; protirelin; thyrotropin-releasing factor; TSH-releasing factor; unnamed protein product
Gene Aliases: Pro-TRH; THR; TRF; TRH01
UniProt ID: (Human) P20396, (Rat) P01150, (Mouse) Q62361
Entrez Gene ID: (Human) 7200, (Rat) 25569, (Mouse) 22044
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cell-cell signaling
hormone-mediated signaling pathway
response to hypoxia
histamine metabolic process
adult walking behavior
response to glucose
negative regulation of glutamate secretion
positive regulation of gamma-aminobutyric acid secretion
positive regulation of insulin secretion
eating behavior
response to ethanol
response to corticosterone
negative regulation of feeding behavior
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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