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Invitrogen
RIOK3 Polyclonal Antibody
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RIOK3 Antibody (PA5-90666) in WB
Western blot analysis of RIOK3 in extracts of various cell lines. Samples were incubated with RIOK3 Polyclonal antibody (Product # PA5-90666) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-90666
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 200-519 of human RIOK3 (NP_0038222)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.39 mg/mL
规格
139 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NHVFNALKQH AYSEERRSAR LHEKKEHSTA EKAVDPKTRL LMYKMVNSGM LETITGCIST GKESVVFHAY GGSMEDEKED SKVIPTECAI KVFKTTLNEF KNRDKYIKDD FRFKDRFSKL NPRKIIRMWA EKEMHNLARM QRAGIPCPTV VLLKKHILVM SFIGHDQVPA PKLKEVKLNS EEMKEAYYQT LHLMRQLYHE CTLVHADLSE YNMLWHAGKV WLIDVSQSVE PTHPHGLEFL FRDCRNVSQF FQKGGVKEAL SERELFNAVS GLNITADNEA DFLAEIEALE KMNEDHVQKN GRKAASFLKD DGDPPLLYDE; Positive Samples: U-251MG, Mouse pancreas
靶标信息
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SUDD, also known as RIOK3 (RIO kinase 3), is a 519 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in a variety of tissues, SUDD catayzes the ATP-dependent phosphorylation of target proteins, thereby influencing signaling events throughout the cell. SUDD is expressed as two isoforms due to alternative splicing events.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RIO kinase 3; Serine/threonine-protein kinase RIO3; sudD, suppressor of bimD6 homolog
基因别名: 1200013N13Rik; D18Ertd331e; E130306C24Rik; Riok3; Sudd
UniProt ID: (Mouse) Q9DBU3
Entrez Gene ID: (Mouse) 66878
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