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Invitrogen
AIM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-91996
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.30 mg/mL
Amount
130 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HeLa, HepG2; Cellular Location: Cytoplasm, Nucleus
Immunogen sequence: HVKPEQKQMV AQQESIREGF QKRCLPVMVL KAKKPFTFET QEGKQEMFHA TVATEKEFFF VKVFNTLLKD KFIPKRIIII ARYYRHSGFL EVNSASRVLD AESDQKVNVP LNIIRKAGET PKINTLQTQP LGTIVNGLFV VQKVTEKKKN ILFDLSDNTG KMEVLGVRNE DTMKCKEGDK VRLTFFTLSK NGEKLQLTSG VHSTIKVI
Target Information
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: absent in melanoma 2; Ifi-210; Interferon-inducible protein 210; Interferon-inducible protein AIM2; Interferon-inducible protein p210; RP11-520H16.3
Gene Aliases: Aim2; Gm1313; Ifi210
UniProt ID: (Mouse) Q91VJ1
Entrez Gene ID: (Rat) 304987, (Mouse) 383619
activation of innate immune response
positive regulation of defense response to virus by host
biological_process
negative regulation of NF-kappaB transcription factor activity
positive regulation of protein oligomerization
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
cellular response to drug
interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
positive regulation of NF-kappaB transcription factor activity
pyroptosis
positive regulation of cysteine-type endopeptidase activity
immune system process
apoptotic process
inflammatory response
innate immune response
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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