Search
Invitrogen
CD1b Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
CD1b Antibody (PA5-93051) in WB
Western blot analysis of CD1b in extracts of NCI-H125 cells. Samples were incubated with CD1b Polyclonal antibody (Product # PA5-93051) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-93051
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human CD1B (NP_0017551)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Amount
13 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SEHAFQGPTS FHVIQTSSFT NSTWAQTQGS GWLDDLQIHG WDSDSGTAIF LKPWSKGNFS DKEVAELEEI FRVYIFGFAR EVQDFAGDFQ MKYPFEIQGI AGCELHSGGA IVSFLRGALG GLDFLSVKNA SCVPSPEGGS RAQKFCALII QYQGIMETVR ILLYETCPRY LLGVLNAGKA DLQRQVKPEA WLSSGPSPGP GRLQLVCHVS GFYPKPVWVM WMRGEQEQQG TQLGDILPNA NWTWYLRATL DVADGEAAGL SCRVKHSSLE GQDIILYWRN PTSIGS; Positive Samples: NCI-H125; Cellular Location: Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: BDCA1; CD1b; CD1b antigen precursor; CD1B antigen, b polypeptide; CD1C antigen; cortical thymocyte antigen CD1B; MGC125990; MGC125991; RP11-101J8.3; RP11-101J8.4; T-cell surface glycoprotein CD1b; unnamed protein product
Gene Aliases: CD1; CD1B; R1
Entrez Gene ID: (Human) 910
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support