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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AHTGAARSCR FRGRHYKREF RLEGEPVALR CPQVPYWLWA SVSPRINLTW HKNDSARTVP GEEETRMWAQ DGALWLLPAL QEDSGTYVCT TRNASYCDKM SIELRVFENT DAFLPFISYP QILTLSTSGV LVCPDLSEFT RDKTDVKIQW YKDSLLLDKD NEKFLSVRGT THLLVHDVAL EDAGYYRCVL TFAHEGQQYN ITRSIELRIK KKKEETIPVI ISPLKTISAS LGSRLTIPCK VFLGTGTPLT TMLWWTANDT HIESAYPGGR VTEGPRQEYS ENNENYIEVP LIFDPVTRED L; Positive Samples: Raji, DU145, HeLa; Cellular Location: Cell membrane, Single-pass type I membrane protein
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ILR2