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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: YMADSETFIS LEECRGHKRA RKRTSMETAL ALEKLFPKQC QVLGIVTPGI VVTPMGSGSN RPQEIEIGES GFALLFPQIE GIKIQPFHFI KDPKNLTLER HQLTEVGLLD NPELRVVLVF GYNCCKVGAS NYLQQVVSTF SDMNIILAGG QVDNLSSLTS EKNPLDIDAS GVVGLSFSGH RIQSATVLLN EDVSDEKTAE AAMQRLKAAN IPEHNTIGFM FACVGRGFQY YRAKGNVEAD AFRKFFPSVP LFGFFGNGEI GCDRIVTGNF ILRKCNEVKD DDLFHSYTTI MALIHLGSSK; Positive Samples: HeLa, MCF-7; Cellular Location: Cytoplasm, Z line, myofibril, sarcomere
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。