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FIGURE: 1 / 1
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: YRLPNEKEIV QGVLQQGTAW RRNQTAARAF RKQMEDCCDP AHLFAMTKMN SPMGKSMWYD GEFLYSFTID NSTYSLFPQA TPFQLPLKKC AVVGNGGILK KSGCGRQIDE ANFVMRCNLP PLSSEYTKDV GSKSQLVTAN PSIIRQRFQN LLWSRKTFVD NMKIYNHSYI YMPAFSMKTG TEPSLRVYYT LSDVGANQTV LFANPNFLRS IGKFWKSRGI HA; Positive Samples: A-549, SGC-7901; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-2, 8-sialyltransferase; Alpha-2,8-sialyltransferase 8A; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Ganglioside GD3 synthase; Ganglioside GT3 synthase; GD3 synthase; sialyltransferase 8 A; Sialyltransferase 8A; Sialyltransferase St8Sia I; sialytransferase St8Sia I; SIAT8-A; ST8Sia I; ST8SiaI
Gene Aliases: 9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a; St8sia1
UniProt ID: (Mouse) Q64687
Entrez Gene ID: (Mouse) 20449
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