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Invitrogen
Phospho-MAX (Ser11) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-MAX (Ser11) Antibody (PA5-97346) in WB
Western blot analysis of Phospho-MAX (Ser11) in extracts of Jurkat cells. Samples were incubated with Phospho-MAX (Ser11) Polyclonal antibody (Product # PA5-97346) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Jurkat cells were treated by serum-starvation overnight. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% BSA.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-97346
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphorylated peptide around S11 of human MAX (NP_0023733)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.31 mg/mL
Amount
31 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Jurkat; Cellular Location: Cell projection, Nucleus, dendrite
Immunogen sequence: VESDE
Target Information
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bHLHd4; Class D basic helix-loop-helix protein 4; Delta-Max; MAX; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; MYC associated factor X; Myc-associated factor X; orf1; Protein max; unnamed protein product
Gene Aliases: BHLHD4; MAX; PDMCS
Entrez Gene ID: (Human) 4149
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
protein dimerization activity
E-box binding
DNA-binding transcription factor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
heterochromatin assembly
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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