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Invitrogen
Collagen III Polyclonal Antibody
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FIGURE: 1 / 5
Collagen III Antibody (PA5-99160) in ICC/IF
Immunofluorescent analysis of Collagen III in BJ cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with Collagen III polyclonal antibody (Product # PA5-99160) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-99160
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human COL3A1(Accession P02461), corresponding to amino acid residues C84-S134.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Collagen III.
Target Information
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-1 type III collagen; alpha-1(III) procollagen; alpha1 (III) collagen; COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; Collagen3; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1; unnamed protein product
Gene Aliases: AW550625; Col3a-1; COL3A1; EDS4A; EDSVASC; mKIAA4231; MMS10-W; Ms10w; PMGEDSV
UniProt ID: (Mouse) P08121, (Rat) P13941
Entrez Gene ID: (Human) 1281, (Mouse) 12825, (Rat) 84032
in utero embryonic development
neuron migration
tissue homeostasis
chondrocyte differentiation
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
heart development
response to radiation
response to wounding
gene expression
peptide cross-linking
layer formation in cerebral cortex
cerebral cortex development
platelet activation
extracellular matrix organization
collagen fibril organization
lung development
transforming growth factor beta1 production
response to cytokine
positive regulation of Rho protein signal transduction
multicellular organism growth
aorta development
limb joint morphogenesis
wound healing
skin development
fibroblast proliferation
elastic fiber assembly
animal organ development
skeletal system morphogenesis
system development
negative regulation of immune response
cartilage development
endochondral bone morphogenesis
aorta smooth muscle tissue morphogenesis
basement membrane organization
fibril organization
response to angiotensin
negative regulation of neuron migration
blood vessel development
extracellular fibril organization
digestive tract development
cellular response to amino acid stimulus
skeletal system development
aging
response to mechanical stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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