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Citations & References (1)

PICHIA BOOK

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Citations & References (1)

Citations & References
Abstract
Mutations in a specific human serum albumin thyroxine binding site define the structural basis of familial dysalbuminemic hyperthyroxinemia.
Authors:Petersen CE, Ha CE, Jameson DM, Bhagavan NV
Journal:J Biol Chem
PubMed ID:8702585
The familial dysalbuminemic hyperthyroxinemia (FDH) phenotype results from a natural human serum albumin (HSA) mutant with histidine instead of arginine at amino acid position 218. This mutation results in an enhanced affinity for thyroxine. Site-directed mutagenesis and a yeast protein expression system were used to synthesize wild type HSA and ... More