CaptureSelect™ C5 Affinity Matrix

CaptureSelect C5 Affinity Matrix has been specifically designed for the depletion or purification of human complement component 5 from human plasma.

Features of this affinity matrix include:

• Highly selective for human complement component 5
• Complex growth media with fetal calf serum can be applied
• Non-animal derived

The high selectivity and yields obtained using CaptureSelect C5 Affinity Matrix enables a robust and efficient purification process with excellent purity obtained in one step.

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

• Matrix: agarose-based
• Average particle size: 65 ± 10 μm
• Ligand: CaptureSelect C5 affinity ligand
• Ligand coupling method: epoxide
• Flow characteristics: 50–200 cm/h (up to 2 bar)
• Formulation buffer: 20% (v/v) ethanol