Hypersil™ PREP HS C8 HPLC Columns
Hypersil™ PREP HS C8 HPLC Columns
Thermo Scientific™

Hypersil™ PREP HS C8 HPLC Columns

Use these preparative columns for scale-up purification with high phase loading. They are suitable for all USP-L7 applications.
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Catalog NumberLength (Metric)Diameter (Metric)Particle SizeColumn Format
41103-05213050 mm2 mm3 μmPreparative Column, Standard
41103-05463050 mm4.6 mm3 μmPreparative Column, Standard
41103-102130100 mm2 mm3 μmPreparative Column, Standard
41103-104630100 mm4.6 mm3 μmPreparative Column, Standard
41103-152130150 mm2 mm3 μmPreparative Column, Standard
41103-154630150 mm4.6 mm3 μmPreparative Column, Standard
41103-252130250 mm2 mm3 μmPreparative Column, Standard
41103-254630250 mm4.6 mm3 μmPreparative Column, Standard
41105-05213050 mm2 mm5 μmPreparative Column, Standard
41105-05463050 mm4.6 mm5 μmPreparative Column, Standard
41105-059070A50 mm10 mm5 μmPreparative Column, Standard
41105-059270A50 mm20 mm5 μmPreparative Column, Standard
41105-059270XL50 mm25 mm5 μmPreparative Column, Xtended Life
41105-102130100 mm2 mm5 μmPreparative Column, Standard
41105-104630100 mm4.6 mm5 μmPreparative Column, Standard
41105-109070A100 mm10 mm5 μmPreparative Column, Standard
41105-109270A100 mm20 mm5 μmPreparative Column, Standard
41105-109270XL100 mm25 mm5 μmPreparative Column, Xtended Life
41105-152130150 mm2 mm5 μmPreparative Column, Standard
41105-154630150 mm4.6 mm5 μmPreparative Column, Standard
41105-159070A150 mm10 mm5 μmPreparative Column, Standard
41105-159270A150 mm20 mm5 μmPreparative Column, Standard
41105-159270XL150 mm25 mm5 μmPreparative Column, Xtended Life
41105-159370A150 mm30 mm5 μmPreparative Column, Standard
41105-159370XL150 mm30 mm5 μmPreparative Column, Xtended Life
41105-159570A150 mm50 mm5 μmPreparative Column, Standard
41105-159570XL150 mm50 mm5 μmPreparative Column, Xtended Life
41105-252130250 mm2 mm5 μmPreparative Column, Standard
41105-254630250 mm4.6 mm5 μmPreparative Column, Standard
41105-259070A250 mm10 mm5 μmPreparative Column, Standard
41105-259270A250 mm20 mm5 μmPreparative Column, Standard
41105-259270XL250 mm25 mm5 μmPreparative Column, Xtended Life
41105-259370A250 mm30 mm5 μmPreparative Column, Standard
41105-259370XL250 mm30 mm5 μmPreparative Column, Xtended Life
41105-259570A250 mm50 mm5 μmPreparative Column, Standard
41105-259570XL250 mm50 mm5 μmPreparative Column, Xtended Life
41110-018823A8 mm10 mm10 μmGuard Column
41110-019023A20 mm10 mm10 μmGuard Column
41110-019323A30 mm10 mm10 μmGuard 1/16 in.
41110-019323B30 mm10 mm10 μmGuard 1/8 in.
41110-029323A30 mm20 mm10 μmGuard 1/16 in.
41110-029323B30 mm20 mm10 μmGuard 1/8 in.
41110-059070A50 mm10 mm10 μmPreparative Column, Standard
41110-059270A50 mm20 mm10 μmPreparative Column, Standard
41110-059270XL50 mm25 mm10 μmPreparative Column, Xtended Life
41110-109070A100 mm10 mm10 μmPreparative Column, Standard
41110-109270A100 mm20 mm10 μmPreparative Column, Standard
41110-109270XL100 mm25 mm10 μmPreparative Column, Xtended Life
41110-159070A150 mm10 mm10 μmPreparative Column, Standard
41110-159270A150 mm20 mm10 μmPreparative Column, Standard
41110-159270XL150 mm25 mm10 μmPreparative Column, Xtended Life
41110-159370A150 mm30 mm10 μmPreparative Column, Standard
41110-159370XL150 mm30 mm10 μmPreparative Column, Xtended Life
41110-159570A150 mm50 mm10 μmPreparative Column, Standard
41110-159570XL150 mm50 mm10 μmPreparative Column, Xtended Life
41110-259070A250 mm10 mm10 μmPreparative Column, Standard
41110-259270A250 mm20 mm10 μmPreparative Column, Standard
41110-259270XL250 mm25 mm10 μmPreparative Column, Xtended Life
41110-259370A250 mm30 mm10 μmPreparative Column, Standard
41110-259370XL250 mm30 mm10 μmPreparative Column, Xtended Life
41110-259570A250 mm50 mm10 μmPreparative Column, Standard
41110-259570XL250 mm50 mm10 μmPreparative Column, Xtended Life
Catalog number 41103-052130
Price (CNY)
3,577.71
飞享价
Ends: 31-Dec-2025
5,042.01
Save 1,464.30 (29%)
Each
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Length (Metric):
50 mm
Diameter (Metric):
2 mm
Particle Size:
3 μm
Column Format:
Preparative Column, Standard
Price (CNY)
3,577.71
飞享价
Ends: 31-Dec-2025
5,042.01
Save 1,464.30 (29%)
Each
Add to cart

Get maximum loading for your scale up from analytical to a prep LC method with Thermo Scientific™ Hypersil™ PREP HS C8 reversed phase preparative HPLC column. With similar selectivity to C18 columns and predictable elution order, C8 columns are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. By providing high surface area particles with a 100Å pore size, and a variety of dimensions including an option for XtendedLife hardware, which improves column lifetime by maintaining a uniform packed bed.

Similar selectivity, less retention than C18 columns

  • Successful retention and separation of moderately hydrophobic analytes.
  • Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
  • C8 (USP L7) selectivity - high surface area particle with 100Å pore size.
  • pH stable from 2 to 8.
  • Maximum temperature of 60°C.

Faster separations

  • Higher analytical throughput compared to C18 alkyl chain chemistry.
  • Quicker compound elution due to reduced hydrophobic interactions.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

  • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
  • Standard threaded hardware for column i.d. < 40mm.
  • Standard flange hardware for column i.d. ≥ 40mm.
  • Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

  • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
  • Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

  • If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
  • Please contact your local sales representative for Customer Specific Orders.
  • Custom built columns are not eligible for returns.
Specifications
Column FormatPreparative Column, Standard
Column TypeReversed Phase
EndcappedYes
Max. Pressure5800 psi (400 bar)
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Stationary PhaseC8
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Carbon Load7%
Diameter (Metric)2 mm
Length (Metric)50 mm
Particle Size3 μm
PhaseReversed Phase
Pore Size100 Å
pH2 to 8
Unit SizeEach