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Citations & References (2)

PCDNA3.1⁄MYC-HIS A,B,C

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Catalog number 430036
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PCDNA3.1⁄MYC-HIS A,B,C
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Unit Size1 each

Citations & References (2)

Citations & References
Abstract
Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.
Authors:Yamaji R, Adamik R, Takeda K, Togawa A, Pacheco-Rodriguez G, Ferrans VJ, Moss J, Vaughan M
Journal:Proc Natl Acad Sci U S A
PubMed ID:10716990
'Two brefeldin A (BFA)-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors, 200-kDa BIG1 and 190-kDa BIG2, were copurified from bovine brain cytosol associated with >670-kDa macromolecular complexes. When observed by immunofluorescence in HeLa S3 and HepG2 cells, endogenous BIG1 and coexpressed BIG2 were distributed in a punctate pattern throughout the cytosol, ... More
MdmX protects p53 from Mdm2-mediated degradation.
Authors:Jackson MW, Berberich SJ.
Journal:Mol Cell Biol
PubMed ID:10629057
'The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or apoptosis. The cellular pathway for releasing normal cells from p53-dependent cell cycle arrest involves the Mdm2 protein. Recently, a p53-binding protein with homology to Mdm2 was ... More