Zeta Plus™ encapsulated filters are single-use depth filters. VR depth filtration provides an economical approach to virus reduction in biotherapeutic processing. Positively charged media combines mechanical entrapment and anion exchange to remove negatively charged contaminants, helping protect chromatography columns or serve as a prefilter to virus‐removal membranes. Available in different sizes to match process scale, supported by a range of single use scale-up capsule devices enabling testing and usage from Lab to Production Scale.
- With specific biological fluids, combined anion exchange and physical entrapment removal mechanisms provide an additional level of viral reduction
- Quality release testing includes a media ion exchange capacity assay
- BC25 Laboratory capsules and Scale-up capsules are ideal for selecting the best media grade using low challenge fluid volume
- A range of scalable capsule sizes aids predictable performance at every stage of drug development – from early stage discovery to commercial production
- Combined ion exchange and physical entrapment virus removal mechanisms provides added level of viral safety and validatable viral log reduction.
- Economical 'bolt-on' separation technology as adjunct or pre-filter to other viral clearance steps provides an added level of validatable viral clearance and can replace or augment chromatography columns or function as prefilter to final virus removal mem
- Viral log reduction.
- Provides orthogonal method of viral clearance.