Human Clariom™ D Complete Assay Kit

Accelerate your biomarker discovery with Clariom D assays for human samples. Clariom D assays provide a highly detailed view of the transcriptome and offer the fastest path to results. Based on industry-leading microarray technology, the novel design of these assays provides transcriptome-wide gene- and exon-level expression profiles with the ability to detect alternative splicing events of coding and long non-coding (lnc)RNA in a single three-day experiment.

Expand your potential to discover novel, informative biomarkers
The number of known transcribed genes has expanded rapidly in recent years, providing more sources for actionable biomarkers, such as transcript variants and lncRNA, that can be used to advance our understanding of disease mechanisms. Such biomarkers can be missed by lengthy, complex, and costly sequencing and targeted expression approaches, leading to irreproducible signatures and wasted time and money.

With full coverage of the transcribed genome including all known coding and non-coding splice variants, compatibility with clinical sample types, and flexible data analysis software, Clariom D assays are the premier tools for translational researchers performing complex expression biomarker discovery studies and wanting the fastest path to robust, clinically relevant, and actionable results.

Get all the data you need
• Rapidly identify complex disease signatures from >540,000 transcripts sourced from public databases to ensure biomarkers are not missed
• Confidently detect genes, exons, and alternative splicing events that give rise to coding RNA and lncRNA isoforms
• Detect rare and low-expressing transcripts otherwise not detected by common sequencing approaches
• Go from data to insight in minutes with intuitive, highly visual, free analysis software

When you have precious samples, get it right the first time
• Utilize RNA from various sample types including blood, cells, and fresh/fresh-frozen tissues
• Preserve sample integrity and reduce data variability with an assay that does not require globin or rRNA removal step

Clariom D solutions are offered in a single sample (cartridge array) format for use on the GeneChip 3000 system and include reagents and fast, simple Transcriptome Analysis Console (TAC) software to analyze and visualize global expression patterns of genes, exons, pathways, and alternative splicing events.

The included GeneChip Hybridization, Wash, and Stain Kit is used with cartridge-format arrays, following the target preparation steps described for 3' eukaryotic, prokaryotic, and exon assays. For convenience, the GeneChip Hybridization, Wash, and Stain Kit reagents are formulated into the fewest number of individual components possible, reducing preparation and handling steps. Most of the reagents are ready-to-use solutions. The kit includes sufficieint solutions to process 30 arrays on the GeneChip Fluidics Station 400 or 450.