Mass Spectrometric Immunoassay (MSIA™), MSIA D.A.R.T.’S, Protein A, Racked

Improve hybrid MS bio-analysis with Thermo Scientific™ Mass Spectrometric Immunoassay (MSIA™), an exclusive Thermo Fisher Scientific workflow solution for proteins and peptides. Enabled through proprietary MSIA D.A.R.T.'S™ technologies, these workflows have demonstrated pg/mL level detection while providing simultaneous qualitative/quantitative data content from complex biological matrix, such as human plasma. Ideal for biologic and biomarker bio-analysis, MSIA provides innovative enablement in the areas of PKPD, DMPK, ADME, Biotransformation (DAR and payload determination), as well as routine biomarker analysis.

• Enables analysis of proteins of interest down to femtomole level
• Streamlined workflow for protein qualitative & quantative bio-analysis
• Employs a proprietary molecular trapping micro-column technology in an easy to use pipette tip housing format
• Drives antibody/antigen binding kinetics and greatly improves assaying of low-abundance protein from a biological sample

• Immunoaffinity column captures protein of interest with improved signal-to-noise ratio
• Superior specificity and assaying characteristics compared to conventional approaches
• Allows for hybrid assaying down to femtomole levels
• Streptavidin and Protein A, G & A/G MSIA D.A.R.T.'S provide end user flexibility to analyze their specific targets of interest
• Custom MSIA D.A.R.T.'S are available upon request
• Optimized workflow solution Insulin (endogenous and therapeutic forms)

Requires:

300μL pipette such as Thermo Scientific™ Versette™ Liquid Handling Platform, Thermo Scientific™ Finnpipette™ Novus i™ Multichannel pipetters (listed in user manual)

Recommended for:

Hybrid mass spectrometry based assays