L-Selenomethionine
L-Selenomethionine
L-Selenomethionine
L-Selenomethionine
Gibco™

L-Selenomethionine

L-Selenomethionine is a naturally occurring amino acid containing selenium that is commonly used for the labeling of proteins to facilitateRead more
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Catalog NumberQuantity
A39247250 mg
Catalog number A39247
Price (CNY)
2,433.79
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Ends: 31-Dec-2025
2,893.00
Save 459.21 (16%)
Each
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Quantity:
250 mg
Price (CNY)
2,433.79
飞享价
Ends: 31-Dec-2025
2,893.00
Save 459.21 (16%)
Each
Add to cart
L-Selenomethionine is a naturally occurring amino acid containing selenium that is commonly used for the labeling of proteins to facilitate structural determination by x-ray crystallography. Selenomethionine is an antioxidant and has been shown to increase glutathione peroxidase activity in endothelial cells.

CAS Number: 3211-76-5
Formula: C5H11NO2Se (molecular weight: 196.11)
Synonyms: (S)-2-amino-4-(methylseleno)butyric acid
Solubility: soluble in water

L-Selenomethionine is supplied in a glass vial containing 250 mg with ≥ 98% minimum purity.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical Name or Material(S)-2-Amino-4-(methylseleno)butyric acid
IUPAC Name(2S)-2-amino-4-(methylselanyl)butanoic acid
InChI KeyRJFAYQIBOAGBLC-BYPYZUCNSA-N
MDL NumberMFCD00037210
Molecular FormulaC5H11NO2Se
Physical FormPowder
Recommended StorageStore at -20°C.

SMILESC[Se]CC[C@H](N)C(O)=O
Shipping ConditionWet Ice
Molecular Weight (g/mol)196.12
Percent Purity>98%
Quantity250 mg
Unit SizeEach

Frequently asked questions (FAQs)

I am performing L-selenomethionine labeling and getting very low protein yields. What could be going wrong?

L-selenomethionine is a known cell toxin. Therefore, it is important to grow cells in the present of this amino acid for the shortest amount of time required to achieve maximal labeling. We recommend adding L-selenomethionine to the culture just prior to transfection (in Expi293 Met (-) Expression Medium). You may also starve cells for 6 hr by culturing cells in Expi293 Met (-) Expression Medium (without supplementation) and then proceed with L-selenomethionine add-back and transfection.

Find additional tips, troubleshooting help, and resources within our Protein Expression Support Center.