InnoviGene™ Suite Software

Applied Biosystems InnoviGene Suite software enables you to analyze and manage capillary electrophoresis sequencing and fragment analysis data generated by Applied Biosystems genetic analyzers. The software provides a streamlined workflow to guide you through uploading and analyzing the data and generating reports.

InnoviGene Suite includes SAE administrator console software with security, audit, and electronic signature (SAE) functions that support compliance with guidelines on electronic records security and prevents unauthorized access to the instrument.

The software is delivered via a download link sent to you after purchase.

Applications within InnoviGene Suite

InnoviGene Suite allows you to create projects for use with other applications that are integrated into the software. These applications enable you to complete an end-to-end workflow using projects that contain related files. The applications available depend on the type of InnoviGene Suite purchased ('sequencing' or 'fragment analysis').

Sequence Quality Check application (Innovigene Suite for sequencing)—enables you to perform the following activities:

• View the quality information for trace files
• Change quality settings and reanalyze trace files
• Perform comparative analysis across multiple trace files

Sequence Identity application (InnoviGene Suite for sequencing)—enables you to view the assembly of multiple files compared to a reference and view basecall mismatches. Specifically, you can perform the following activities with the application:

• Basecalling, quality value assignment, and mixed base identification
• Trimming low-quality ends from each sequence, if the setting is active
• Identifying poor-quality samples
• Assembling the samples against the reference sequence and generating a specimen consensus sequence
• Reviewing the basecalling quality values and consensus quality values
• Identifying mismatches by aligning and comparing specimen sequences to the reference sequence. A mismatch is a position in the specimen that does not match with the reference sequence. Mismatches include base changes, insertions, and deletions.
• Assigning specimen status based on alignment with the reference sequence and coverage criteria
• Editing basecalls in samples or the consensus
• Generating reports and results for export in CSV format

STR Typing application (InnoviGene Suite for fragment analysis)—the STR Typing application is genotyping software that uses short tandem repeat (STR) data. It enables you to perform the following activities:

• Analyze a mixture of DNA fragments, separated by size
• Provide a profile of the separation
• Calculate the sizes of the fragments
• Determine the alleles present in fragment analysis sample (FSA) files