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Citations & References (33)
Invitrogen™
ATTO-TAG™ CBQCA Derivatization Reagent (CBQCA; 3-(4-Carboxybenzoyl)quinoline-2-Carboxaldehyde)
The ATTO-TAG™ CBQCA derivatization reagent (CBQCA; 3-(4carboxybenzoyl)quinoline- 2-carboxaldehyde) reacts specifically with primary amines to form conjugates that can be analyzedRead more
| Catalog Number | Quantity |
|---|---|
| A6222 also known as A-6222 | 10 mg |
Catalog number A6222
also known as A-6222
Price (CNY)
4,565.00
飞享价
Ends: 31-Dec-2025
5,802.00Save 1,237.00 (21%)
Each
Quantity:
10 mg
Price (CNY)
4,565.00
飞享价
Ends: 31-Dec-2025
5,802.00Save 1,237.00 (21%)
Each
The ATTO-TAG™ CBQCA derivatization reagent (CBQCA; 3-(4carboxybenzoyl)quinoline- 2-carboxaldehyde) reacts specifically with primary amines to form conjugates that can be analyzed by electrophoretic or chromatographic methods. The resulting products of CBQCA are maximally excited at 450 nm or by the 442 nm spectral line of the He-Cd laser and have emission maxima at ∼550 nm. In capillary zone electrophoresis (CZE), the sensitivity of detection of ATTO-TAG™ CBQCA conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for researcher, diagnostic and forensic applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
For Use With (Application)Cell Viability, Proliferation and Function; Protein Electrophoresis and Western Blotting
Label or DyeATTO-TAG CBQCA
Quantity10 mg
Reactive MoietyAldehyde
Shipping ConditionRoom Temperature
TargetPrimary Amine
FormSolid
Product LineATTO-TAG
TypeDerivatization Kits and Reagents
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Frequently asked questions (FAQs)
Can CBQCA (3-(4carboxybenzoyl) quinoline- 2-carboxaldehyde) be used to label reducing sugars?
Can NaCN be used instead of KCN in the CBQCA (3-(4carboxybenzoyl) quinoline- 2-carboxaldehyde) assay?
Citations & References (33)
Citations & References
Abstract
CBQCA assay of primary amine losses during hemodialysis.
Journal:Clin Chim Acta
PubMed ID:11412827
Nitrogen loss during hemodialysis is an important issue since all steps taken to improve clearance of urea will also increase loss of amino acids and other normally recyclable sources of nitrogen. Most dialyzers exclude albumin and other proteins, which react well with dyes commonly employed to measure protein, but do
Derivatization in capillary electrophoresis.
Journal:J Chromatogr A
PubMed ID:9646486
'In recent years capillary electrophoresis (CE) has been developed into a versatile separation technique, next to gas and liquid chromatography (LC), well suited for the determination of a wide variety of e.g., pharmaceutical, biomedical and environmental samples. The main advantages of CE over chromatographic separation techniques are its simplicity and
Capillary electrophoresis with laser-induced fluorescence detection: a sensitive method for monitoring extracellular concentrations of amino acids in the periaqueductal grey matter.
Journal:J Neurosci Methods
PubMed ID:8815306
'The use of capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) for the analysis of microdialysate samples from the periaqueductal grey matter (PAG) of freely moving rats is described. By employing 3-(4-carboxybenzoyl)-2-quinoline-carboxaldehyde (CBQCA) as a derivatization agent, we simultaneously monitored the concentrations of 8 amino acids (arginine, glutamine, valine, gamma-amino-n-butyric acid
Mycothiol biosynthesis and metabolism. Cellular levels of potential intermediates in the biosynthesis and degradation of mycothiol in mycobacterium smegmatis.
Journal:J Biol Chem
PubMed ID:9804803
'Mycothiol (MSH; 1-D-myo-inosityl-2-(N-acetyl-L-cysteinyl)amido-2-deoxy-alpha-D- glucop yranoside (AcCys-GlcN-Ins)) is a novel thiol produced at millimolar levels by mycobacteria and other actinomycetes that do not make glutathione. We developed methods to determine the major components of MSH (AcCys, Cys-GlcN, AcCys-GlcN, Cys-GlcN-Ins, GlcN-Ins) in cell extracts. Mycobacterium smegmatis was shown to produce measurable levels
Identification of a recombinant synaptobrevin-thioredoxin fusion protein by capillary zone electrophoresis using laser-induced fluorescence detection.
Journal:J Chromatogr B Biomed Sci Appl
PubMed ID:9271130
'Capillary zone electrophoresis (CZE) was utilized to identify a synaptobrevin-thioredoxin fusion protein (TSB-51). TSB-51 is a substrate for cleavage by botulinum toxin B at the Q(76)-F(77) site. TSB-51 was derivatized with a fluorophore, CBQCA [3-(4-carboxy-benzoyl)-2-quinoline-carboxaldehyde], for 4 h at room temperature. Optimal conditions for CZE separation of the TSB-51-CBQCA complex