Orbitrap™ Astral™ Mass Spectrometers

Realize the promise of proteomics at scale to better understand biology and disease mechanisms with the novel technology of the Thermo Scientific™ Orbitrap™ Astral™ mass spectrometer. Expect whole proteome coverage at a depth of 12,000 proteins in an hour, the sensitivity to accurately and precisely quantify over 3,000 proteins from 80 single cells in a day, and the throughput to analyze over a million protein groups across 180 samples in a day. These groundbreaking capabilities empower you to comprehend the dynamic, temporal, and spatial complexity of biology.

Rethink what is possible.

Faster throughput

Identify over 8,000 proteins with an 8-minute injection-to-injection cycle

Deeper coverage

Unlock near whole-proteome depth of coverage with the identification of 12,000 proteins in 1 hour from a single-shot experiment

Higher sensitivity

Increase throughput and depth of coverage with higher sensitivity by identifying over 5,000 proteins from 250 pg of HeLa at a rate of 80 samples per day

Accurate and precise quantitation

Achieve accurate and precise quantitation with a large dynamic range for Label-Free Quantitation (LFQ) using Data-Independent Acquisition (DIA) and achieve faster throughput and deeper coverage with multiplexed quantitation using Tandem Mass Tags (TMT)