6-TAMRA, SE (6-Carboxytetramethylrhodamine, Succinimidyl Ester), single isomer

Citations & References (239)

Invitrogen™

6-TAMRA, SE (6-Carboxytetramethylrhodamine, Succinimidyl Ester), single isomer

Catalog Number	Quantity
C6123 also known as C-6123	5 mg

Catalog number C6123

also known as C-6123

Price (CNY)

6,746.00

Quantity:

Price (CNY)

6,746.00

The isomeric 6-TAMRA, SE is an amine-reactive form of tetramethylrhodamine. The single-isomer preparations of TAMRA are most important for high-resolution techniques such as DNA sequencing and capillary electrophoresis. 6-TAMRA is one of the traditional fluorophores used for automated DNA sequencing.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical ReactivityAmine

Label or DyeTAMRA™ Isomers, TMR (Tetramethylrhodamine)

Product Type6-TAMRA SE

Quantity5 mg

Reactive MoietyActive Ester, Succinimidyl Ester

Shipping ConditionRoom Temperature

Label TypeClassic Dyes

Unit SizeEach

Contents & Storage

Store in freezer (-5 to -30°C) and protect from light.

Citations & References (239)

Citations & References

Abstract

Multiplex detection of single-nucleotide variations using molecular beacons.

Authors:Marras SA,Kramer FR,Tyagi S

Journal:Genetic analysis : biomolecular engineering

PubMed ID:10084107

Quantitative polymerase chain reaction-based homogeneous assay with fluorogenic probes to measure c-erbB-2 oncogene amplification.

Authors:Gelmini S, Orlando C, Sestini R, Vona G, Pinzani P, Ruocco L, Pazzagli M

Journal:Clin Chem

PubMed ID:9166227

We describe a PCR-based assay for determining c-erbB-2 oncogene amplification in breast cancer in which we use the TaqMan system. Two fluorogenic probes anneal to the target between primers for c-erbB-2 and beta-globin genes and contain both a reporter dye (6-carboxy-fluorescein) and a quencher dye (6-carboxy-tetramethyl-rhodamine). During the extension phase ... More

DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments.

Authors:Lee LG, Connell CR, Woo SL, Cheng RD, McArdle BF, Fuller CW, Halloran ND, Wilson RK

Journal:Nucleic Acids Res

PubMed ID:1598205

The incorporation of fluorescently labeled dideoxynucleotides by T7 DNA polymerase is optimized by the use of Mn2+, fluorescein analogs and four 2'-deoxyribonucleoside 5'-O-(1-thiotriphosphates) (dNTP alpha S's). The one-tube extension protocol was tested on single-stranded templates, as well as PCR fragments which were made single-stranded by digestion with T7 gene 6 ... More

Fluorescence resonance energy transfer analysis of the structure of the four-way DNA junction.

Authors:Clegg RM, Murchie AI, Zechel A, Carlberg C, Diekmann S, Lilley DM

Journal:Biochemistry

PubMed ID:1591245

We have carried out fluorescence resonance energy transfer (FRET) measurements on four-way DNA junctions in order to analyze the global structure and its dependence on the concentration of several types of ions. A knowledge of the structure and its sensitivity to the solution environment is important for a full understanding ... More

A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes.

Authors:Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG

Journal:J Biol Chem

PubMed ID:12511563

T lymphocytes with unusually high expression of the voltage-gated Kv1.3 channel (Kv1.3(high) cells) have been implicated in the pathogenesis of experimental autoimmune encephalomyelitis, an animal model for multiple sclerosis. We have developed a fluoresceinated analog of ShK (ShK-F6CA), the most potent known inhibitor of Kv1.3, for detection of Kv1.3(high) cells ... More

View all 6-TAMRA, SE (6-Carboxytetramethylrhodamine, Succinimidyl Ester), single isomer citations