ChargeSwitch™ Forensic DNA Purification Kit
ChargeSwitch™ Forensic DNA Purification Kit
Invitrogen™

ChargeSwitch™ Forensic DNA Purification Kit

Highest sensitivity for poor or environmentally degraded samples• Fully validated for forensic Single Tandem Repeat (STR) analysis• Optimized for rapidRead more
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Catalog NumberNo. of Reactions
CS11200100 Preps
CS1120010
also known as CS11200-10
960 Preps
Catalog number CS11200
Price (CNY)
4,547.00
飞享价
Ends: 31-Dec-2025
5,507.00
Save 960.00 (17%)
Each
Add to cart
No. of Reactions:
100 Preps
Price (CNY)
4,547.00
飞享价
Ends: 31-Dec-2025
5,507.00
Save 960.00 (17%)
Each
Add to cart

Highest sensitivity for poor or environmentally degraded samples

• Fully validated for forensic Single Tandem Repeat (STR) analysis
• Optimized for rapid manual or fully automated sample processing

The ChargeSwitch™ Forensic DNA Purification Kit affords the highest sensitivity and robustness. This kit is designed to accommodate all forensic crime scene sample types for STR profiling. This kit includes all the necessary reagents for the number of preps listed and requires the use of a magnetic accessory. Please see the Accessories Chapter (Chapter 6) to select the best magnetic accessory for your needs.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use With (Application)Forensic
High-throughput CompatibilityHigh-throughput Compatible
No. of Reactions100 Preps
Product LineChargeSwitch™
Product TypeForensic DNA Purification Kit
Quantity100 Preps
Sample TypeForensic Sample
Shipping ConditionRoom Temperature
TargetGenomic DNA
Test Time15 min.
FormatKit
Isolation TechnologyChargeSwitch Chemistry
Unit SizeEach
Contents & Storage

All components of the ChargeSwitch™ Forensic DNA Purification Kits are shipped at room temperature. Upon receipt, store the Proteinase K at 4°C. Store all other components at room temperature. All components are guaranteed stable for 6 months, if stored properly.

Components:
• ChargeSwitch™ Lysis Buffer (L13)
• ChargeSwitch™ Magnetic Beads
• Proteinase K (20 mg/mL in 50 mM Tris-HCl, pH 8.5, 5 mM CaCl2, 50% glycerol)
• ChargeSwitch™ Purification Buffer (N5)
• ChargeSwitch™ Wash Buffer (W12)
• ChargeSwitch™ Elution Buffer (E5; 10 mM Tris-HCl, pH 8.5)

Frequently asked questions (FAQs)

I used water to elute my plasmid instead of the Elution Buffer with my ChargeSwitch kit, but saw very low plasmid yield. Why is this?

We strongly recommend using the Elution Buffer provided in the kit, and do not recommend elution with water. If you need to elute in any other buffer, be sure to use a buffer of pH 8.5-9.0 for efficient DNA elution.

What is the difference between the ChargeSwitch Pro kit and the Charge-Switch Pro filter kit?

The filter kit is based upon a dual nested column design, which facilitates the fastest and simplest protocol for obtaining high quality plasmid (less than 10 EU/µg DNA). Modified wash buffer 1 removes more endotoxin.

What is the typical yield when using the ChargeSwitch Pro Filter Plasmid Mini or Midi Kits?

The typical yield is 25 µg from a 5 mL culture for the ChargeSwitch Pro mini kit, 200 µg from a 25 mL culture for the midi kit, and 800 µg from a 100 mL culture from the maxi kit. The plasmid size range for the kits is typically 3-9 kb.

Do you offer any kits for forensic DNA purification?

Yes, we offer our ChargeSwitch Forensic DNA Purification Kit. Please read more about DNA extraction here (http://www.thermofisher.com/us/en/home/life-science/dna-rna-purification-analysis/dna-extraction/genomic-dna-extraction/forensic-dna-extraction.html).

How does ChargeSwitch technology work?

Based on a patented switchable chemistry, ChargeSwitch purification utilizes the charge on a solid surface for nucleic acid capture. At lower pH, the surface chemistry holds a positive charge and attracts nucleic acid. At higher pH, the surface chemistry is neutral and any bound nucleic acid is released.