Dansyl Ethylenediamine, 5-Dimethylaminonaphthalene-1-(N-(2-Aminoethyl))sulfonamide
Dansyl Ethylenediamine, 5-Dimethylaminonaphthalene-1-(<i>N</i>-(2-Aminoethyl))sulfonamide
Invitrogen™

Dansyl Ethylenediamine, 5-Dimethylaminonaphthalene-1-(N-(2-Aminoethyl))sulfonamide

The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff baseRead more
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Catalog NumberQuantity
D112
also known as D-112
100 mg
Catalog number D112
also known as D-112
Price (CNY)
3,795.00
Each
Add to cart
Quantity:
100 mg
Price (CNY)
3,795.00
Each
Add to cart
The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC (E2247). This fluorophore is lipophilic and environmentally-sensitive.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityCarboxylic Acid, Ketone, Aldehyde
Label or DyeDansyl
Product TypeDansyl Ethylenediamine
Quantity100 mg
Reactive MoietyAmine, Ethylenediamine
Shipping ConditionRoom Temperature
Label TypeClassic Dyes
Unit SizeEach
Contents & Storage
Store at room temperature and protect from light.

Citations & References (26)

Citations & References
Abstract
Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for rho GTPases.
Authors:Schmidt G,Goehring UM,Schirmer J,Lerm M,Aktories K
Journal:The Journal of biological chemistry
PubMed ID:10542213
Enkephalin analogs. Introduction of sterochemical constraints, metal binding sites and fluorescent groups.
Authors:Nagaraj R, Sudha TS, Shivaji S, Balaram P
Journal:FEBS Lett
PubMed ID:499510
Physical and biological properties of fluorescent dansylated bile salt derivatives: the role of steroid ring hydroxylation.
Authors:Crawford JM, Lin YJ, Teicher BA, Narciso JP, Gollan JL
Journal:Biochim Biophys Acta
PubMed ID:1892892
'The hydroxyl groups of bile salts play a major role in determining their physical properties and physiologic behavior. To date, no fluorescent bile salt derivatives have been prepared which permit evaluation of the functional role of the steroid ring. We have prepared five fluorescent cholanoyl derivatives using a dansyl-ethylene diamine ... More
Modification of oligosaccharide antenna flexibility induced by exoglycosidase trimming.
Authors:Rice KG, Wu P, Brand L, Lee YC
Journal:Biochemistry
PubMed ID:8343515
'We have investigated the solution conformation of a triantennary glycopeptide using resonance energy transfer [Rice et al. (1991) Biochemistry 30, 6646-6655]. Triantennary glycopeptide was derivatized with a donor fluorophore on the N-terminus and with an acceptor fluorophore attached individually to each terminal galactose residue, resulting in three isomeric donor-acceptor pairs. ... More
Conformational studies of glycopeptides by energy transfer. Introduction of fluorophore at specific branches of biantennary glycopeptides.
Authors:Lee KB, Lee YC
Journal:J Biol Chem
PubMed ID:8576139
'Biantennary glycopeptides from bovine fibrinogen were fluorescence labeled at each branch specifically for conformational studies by fluorescence energy transfer. Glycopeptides (by Pronase digestion) were separated by anion-exchange chromatography based on the degree of sialylation. The major monosialyl biantennary glycopeptides (see below) were used as substrates for galactose oxidase and periodate ... More