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Citations & References (23)
Invitrogen™
DQ™ Ovalbumin - Special Packaging
DQ ovalbumin is a fluorogenic substrate for proteases. A strong fluorescence quenching effect is observed when proteins are heavily labeledRead more
| Catalog Number | Quantity |
|---|---|
| D12053 | 5 x 1 mg |
Catalog number D12053
Price (CNY)
5,118.00
飞享价
Ends: 31-Dec-2025
6,938.00Save 1,820.00 (26%)
Each
Quantity:
5 x 1 mg
Price (CNY)
5,118.00
飞享价
Ends: 31-Dec-2025
6,938.00Save 1,820.00 (26%)
Each
DQ ovalbumin is a fluorogenic substrate for proteases. A strong fluorescence quenching effect is observed when proteins are heavily labeled with BODIPY dyes. Upon hydrolysis of the DQ ovalbumin to single, dye-labeled peptides by proteases, this quenching is relieved, producing brightly fluorescent products.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Label or DyeBODIPY™ FL
Product LineDQ
Product TypeAntigen processing and presentation studies
Quantity5 x 1 mg
Shipping ConditionRoom Temperature
SubstrateProtease Substrate
Detection MethodFluorescence
FormSolid
Substrate PropertiesProtein-Based Substrate
Target EnzymeProteases
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Frequently asked questions (FAQs)
Do you have an alternative for DQ Ovalbumin – Special Packaging (Cat. No. D12053) that can be purchased in the EU?
Citations & References (23)
Citations & References
Abstract
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Journal:Nat Immunol
PubMed ID:14716310
'Microbial DNA sequences containing unmethylated CpG dinucleotides activate Toll-like receptor 9 (TLR9). We have found that TLR9 is localized to the endoplasmic reticulum (ER) of dendritic cells (DCs) and macrophages. Because there is no precedent for immune receptor signaling in the ER, we investigated how TLR9 is activated. We show
Carbohydrate oxidation acidifies endosomes, regulating antigen processing and TLR9 signaling.
Journal:J Immunol
PubMed ID:20200279
'Phagocytes kill encapsulated microbes through oxidative cleavage of surface carbohydrates, releasing glycan fragments and microbial contents that serve as ligands for immune receptors, which tailor the immune response against the offending pathogen. The glycan fragments serve as MHC class II (MHC II) ligands and innate receptor agonists, whereas microbial proteins
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Journal:Nat Immunol
PubMed ID:18604214
'Inhalation of silica crystals causes inflammation in the alveolar space. Prolonged exposure to silica can lead to the development of silicosis, an irreversible, fibrotic pulmonary disease. The mechanisms by which silica and other crystals activate immune cells are not well understood. Here we demonstrate that silica and aluminum salt crystals
Digestion assays in allergenicity assessment of transgenic proteins.
Journal:Environ Health Perspect
PubMed ID:16882518
'The food-allergy risk assessment for transgenic proteins expressed in crops is currently based on a weight-of-evidence approach that holistically considers multiple lines of evidence. This approach recognizes that no single test or property is known to distinguish allergens from nonallergens. The stability of a protein to digestion, as predicted by
Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients.
Journal:PLoS One
PubMed ID:20027300
'BACKGROUND: Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations in the CHM gene, which encodes Rab escort protein-1 (REP-1), an escort protein involved in the prenylation of Rabs. Under-prenylation of certain Rabs, as a result of loss of function mutations in REP-1, could affect vesicular trafficking, exocytosis and