Ethambutol dihydrochloride

An antibacterial agent | CAS: 1070-11-7 | C10H26Cl2N2O2 | 277.23 g/mol

Catalog Number	Quantity
J60695.14 also known as J60695-14	25 g

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Catalog number J60695.14

also known as J60695-14

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Chemical Identifiers

CAS1070-11-7

IUPAC Namedihydrogen (2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl]amino}ethyl)amino]butan-1-ol dichloride

Molecular FormulaC10H26Cl2N2O2

InChI KeyAUAHHJJRFHRVPV-BZDVOYDHSA-N

SMILES[H+].[H+].[Cl-].[Cl-].CC[C@@H](CO)NCCN[C@@H](CC)CO

Specifications

Loss on Drying0.5% max.

Assay (unspecified)Specific rotation: +6.0 to +6.7 (c=10 in water at 25?)

Trace Metals20 ppm max.

Assay (unspecified)98.0-100.5%

Ethambutol dihydrochloride it acts as a tuberculostatic antibacterial agent. It is used to treat tuberculosis in combination with other antibiotics to reduce the development of drug resistance. It has been used to study multidrug-resistant tuberculosis (MDR-TB) in highest-incidence-rate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Slightly soluble in water

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

RUO – Research Use Only

General References:

Byeong-Ho Jeong et. al. Intermittent Antibiotic Therapy for Nodular Bronchiectatic Mycobacterium avium Complex Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2015, 191,(1), 96-103.
K H Khoo et. Al. Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis. Inhibition of arabinan biosynthesis by ethambutol. Journal of Biological Chemistry. 1996, 271,(45), 28682-28690.