Ouabain octahydrate, 95%

Inhibitor of sodium-potassium-dependent ATPase | CAS: 11018-89-6 | C29H60O20 | 728.779 g/mol

Catalog Number	Quantity
J60724.03 also known as J60724-03	1 g

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Catalog number J60724.03

also known as J60724-03

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Chemical Identifiers

CAS11018-89-6

IUPAC Name4-[(1R,7S,9R,9bS,10R)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one octahydrate

Molecular FormulaC29H60O20

InChI KeyTYBARJRCFHUHSN-HMNHGHQSSA-N

SMILESO.O.O.O.O.O.O.O.CC1OC(O[C@H]2C[C@@H](O)C3(CO)[C@H]4[C@H](O)CC5(C)[C@H](CCC5(O)C4CCC3(O)C2)C2=CC(=O)OC2)C(O)C(O)C1O

Specifications

Appearance (Color)White to off-white to pale yellow

FormPowder

Assay (UV/vis)≥94.0%

Loss on Drying14.5-22.0%

Ouabain, as well as other endogenous digitalis-like compounds, can down-regulate the expression of 14-3-3 proteins in rat lens.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ouabain, as well as other endogenous digitalis-like compounds, can down-regulate the expression of 14-3-3 proteins in rat lens.

Solubility
Soluble in water.

Notes
Protect from light. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

RUO – Research Use Only

General References:

D.I. de Vasconcelos, et al. Anti-inflammatory and antinociceptive activity of ouabain in mice. Mediators Inflamm. 2011, 123,(5), 912-925.
B Hellman, J Sehlin, IB Taljedal. Calcium uptake by pancreatic -cells as measured with the aid of 45 Ca and mannitol- 3 H. American Journal of Physiology . 1971, 221, 1795-1801.