Miconazole, 97%

Name: Miconazole, 97%
SKU: J60872.06

Inhibits cytochrome P450-dependent 14-alpha-demethylase | CAS: 22916-47-8 | C18H14Cl4N2O | 416.12 g/mol

Change view

Quantity:

1 g

5 g

25 g

Try the chem dex^TM web app

This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.

Catalog number J60872.06

also known as J60872-06

Price (CNY)

Quantity:

5 g

Request bulk or custom format

Chemical Identifiers

CAS22916-47-8

IUPAC Name1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

Molecular FormulaC18H14Cl4N2O

InChI KeyBYBLEWFAAKGYCD-UHFFFAOYNA-N

SMILESClC1=CC=C(COC(CN2C=CN=C2)C2=CC=C(Cl)C=C2Cl)C(Cl)=C1

Specifications

Specification Sheet

Melting Point75.0-82.0°C

Appearance (Color)White

FormPowder

Assay from Supplier's CofA≥96.0% (HPLC)

Miconazole, is used as an antifungal inhibitor of aromatase. Miconazole has been shown to promote remyelination of neurons in chronic progressive multiple sclerosis mouse models. Miconazole is mainly used externally for the treatment of athlete's foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis. It is also used in photography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Freely soluble in alcohols or acetone. Also soluble in DMF or chloroform. Insoluble in water

Notes
Protect from light. Store in well-closed containers.

RUO – Research Use Only

General References:

White TC.; Marr KA.; Bowden RA. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev. 1998, 11,(2), 382-402.
Ghannoum MA.; Rice LB. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin Microbiol Rev. 1999, 12,(4), 501-17.