Felodipine

A dihydropyridine calcium channel blocker | CAS: 72509-76-3 | C18H19Cl2NO4 | 384.253 g/mol

Catalog Number	Quantity
J61195.MC also known as J61195-MC	100 mg

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Catalog number J61195.MC

also known as J61195-MC

Price (CNY)

Quantity:

100 mg

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Chemical Identifiers

CAS72509-76-3

IUPAC Name3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Molecular FormulaC18H19Cl2NO4

InChI KeyRZTAMFZIAATZDJ-UHFFFAOYNA-N

SMILESCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC(Cl)=C1Cl)C(=O)OC

Specifications

Purity≥95.0%

Mass SpecConforms

FormPowder or crystals or crystalline powder

Appearance (Color)Yellow to yellow-green

Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.

Solubility
Soluble in DMSO. Insoluble in water

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

RUO – Research Use Only

General References:

Ljung. Vascular selectivity of felodipine: experimental pharmacology. J.Cardiovasc.Pharmacol. 1990, 15,(4), S11-6.
Furukawa et al. Selectivities of dihydropyridine derivatives in blocking Ca2+ channel subtypes expressed inXenopus oocytes. J.Pharmacol.Exp.Ther. 1999, 291,(2), 464-73.