Adenosine-3',5'-cyclic monophosphate sodium salt, 99%
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Adenosine-3',5'-cyclic monophosphate sodium salt, 99%
Adenosine-3',5'-cyclic monophosphate sodium salt, 99%
Adenosine-3',5'-cyclic monophosphate sodium salt, 99%
Thermo Scientific Chemicals

Adenosine-3',5'-cyclic monophosphate sodium salt, 99%

CAS: 37839-81-9 | C10H11N5NaO6P | 351.19 g/mol
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Quantity:
250 mg
1 g
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Catalog number J62174.MD
also known as J62174-MD
Price (CNY)
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Quantity:
250 mg
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Chemical Identifiers
CAS37839-81-9
IUPAC Namesodium (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate
Molecular FormulaC10H11N5NaO6P
InChI KeyBXJBFCKTIWRKMQ-GWKNMROSNA-M
SMILES[Na+].NC1=C2N=CN([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C2=NC=N1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to pale cream
FormCrystals or powder or crystalline powder
Assay from Suppliers CofA≥98.5%
Adenosine 3?,5?-cyclic monophosphate sodium salt monohydrate is used as an activator of protein kinase A (PKA) . A key regulator of many cellular reactions. Released in response to hormonal stimulation. . Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is used as an activator of protein kinase A (PKA) . A key regulator of many cellular reactions. Released in response to hormonal stimulation. . Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.

Solubility
Soluble in water (50 mg/ml).

Notes
Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
RUO – Research Use Only

General References:

  1. W Epstein.; LB Rothman-Denes. Adenosine 3': 5'-cyclic monophosphate as mediator of catabolite repression in Escherichia coli. PNAS.1975, 72, (6), 2300-2304.
  2. CM Szego.; JS Davis. Adenosine 3', 5'-monophosphate in rat uterus: acute elevation by estrogen. PNAS.1967, 58, (4), 1711-1718.