Ketoconazole, 98%

Name: Ketoconazole, 98%
SKU: J63367.06

Potent inhibitor of cytochrome P450c17 | CAS: 65277-42-1 | C26H28Cl2N4O4 | 534.452 g/mol

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25 g

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Catalog number J63367.06

also known as J63367-06

Price (CNY)

Quantity:

5 g

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Chemical Identifiers

CAS65277-42-1

IUPAC Name1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one

Molecular FormulaC26H28Cl2N4O4

InChI KeyXMAYWYJOQHXEEK-ZEQKJWHPSA-N

SMILESCC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1

Specifications

Specification Sheet

Appearance (Color)White

Assay from Supplier's CofA≥97.5%

FormPowder

Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent.

Solubility
Soluble in DMSO, ethanol, chloroform, water, and methanol.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

RUO – Research Use Only

General References:

Mikihisa Takano.; Risa Hasegawa.; Takeshi Fukuda.; Ryoko Yumoto.; Junya Nagai.; Teruo Murakami. Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. European Journal of Pharmacology.1998, 358, (3), 289-294.
Nick E Goeders.; Rachel L Peltier.; Glenn F Guerin. Ketoconazole reduces low dose cocaine self-administration in rats.Drug and Alcohol Dependence.1998, 53, (1), 67-77.