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Thermo Scientific Chemicals
Cetirizine dihydrochloride, 99+%
CAS: 83881-52-1 | C21H27Cl3N2O3 | 461.81 g/mol
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Chemical Identifiers
CAS83881-52-1
IUPAC Namedihydrogen 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid dichloride
Molecular FormulaC21H27Cl3N2O3
InChI KeyPGLIUCLTXOYQMV-UHFFFAOYNA-N
SMILES[H+].[H+].[Cl-].[Cl-].OC(=O)COCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
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Specifications
Specification Sheet
Specification SheetFormPowder or crystalline powder
Appearance (Color)White to pale cream
Assay from Supplier's CofA≥99.0% (HPLC)
pH1.20-1.80 (5.0% solution in water)
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
Solubility
Soluble in water, DMSO, ethanol, and methanol.
Notes
Keep container tightly closed. Store away from oxidizing agents.
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
Solubility
Soluble in water, DMSO, ethanol, and methanol.
Notes
Keep container tightly closed. Store away from oxidizing agents.
RUO – Research Use Only