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Citations & References (6)
Invitrogen™
QSY™ 21 Carboxylic Acid, Succinimidyl Ester
QSY™ 21 carboxylic acid, succinimidyl ester
| Catalog Number | Quantity |
|---|---|
| Q20132 | 5 mg |
Catalog number Q20132
Price (CNY)
5,299.00
Each
Quantity:
5 mg
Price (CNY)
5,299.00
Each
The amine-reactive quencher, QSY™ 21 succinimidyl ester has a broad and intense absorption (∼661 nm maxima) but no fluorescence making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
Label or DyeQSY™ 21
Product TypeSuccinimidyl Ester
Quantity5 mg
Reactive MoietyActive Ester, Succinimidyl Ester
Shipping ConditionWet Ice
Label TypeQuencher Dyes
Product LineQSY
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Citations & References (6)
Citations & References
Abstract
Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice.
Journal:Proc Natl Acad Sci U S A
PubMed ID:20566877
'The slow growth rate and genetic intractability of tubercle bacilli has hindered progress toward understanding tuberculosis, one of the most frequent causes of death worldwide. We overcame this roadblock through development of near-infrared (NIR) fluorogenic substrates for beta-lactamase, an enzyme expressed by tubercle bacilli, but not by their eukaryotic hosts,
An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging.
Journal:Bioconjug Chem
PubMed ID:19331388
'Apoptosis is required for normal cellular homeostasis, and deregulation of the apoptotic process is implicated in various diseases. Previously, we developed a cell-penetrating near-infrared fluorescence (NIRF) probe based on an activatable strategy to detect apoptosis-associated caspase activity in vivo. This probe consisted of a cell-penetrating Tat peptide conjugated to an
Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin
Journal:Bioconjug Chem
PubMed ID:19072537
In vivo molecular cancer imaging with monoclonal antibodies has great potential not only for cancer detection, but also for cancer characterization. However, the prolonged retention of intravenously injected antibody in the blood causes low target tumor-to-background ratio (TBR). Avidin has been used as a
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes.
Journal:Nat Chem Biol
PubMed ID:17828252
We have generated a series of quenched near-infrared fluorescent activity-based probes (qNIRF-ABPs) that covalently target the papain-family cysteine proteases shown previously to be important in multiple stages of tumorigenesis. These 'smart' probes emit a fluorescent signal only after covalently modifying a specific protease target. After intravenous injection of NIRF-ABPs into
Time-resolved Förster-resonance-energy-transfer DNA assay on an active CMOS microarray.
Journal:Biosens Bioelectron
PubMed ID:18515059
We present an active oligonucleotide microarray platform for time-resolved Förster-resonance-energy-transfer (TR-FRET) assays. In these assays, immobilized probe is labeled with a donor fluorophore and analyte target is labeled with a fluorescence quencher. Changes in the fluorescence decay lifetime of the donor are measured to determine the extent of hybridization. In