Tetramethylrhodamine, Ethyl Ester, Perchlorate (TMRE)
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Tetramethylrhodamine, Ethyl Ester, Perchlorate (TMRE)
Invitrogen™

Tetramethylrhodamine, Ethyl Ester, Perchlorate (TMRE)

Tetramethylrhodamine, ethyl ester (TMRE) is a cell-permeant, cationic, red-orange fluorescent dye that is readily sequestered by active mitochondria.Dissolve the dyeRead more
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Catalog NumberQuantity
T66925 mg
Catalog number T669
Price (CNY)
2,559.00
Online Exclusive
Ends: 31-Dec-2025
3,467.00
Save 908.00 (26%)
25 mg
Add to cart
Quantity:
25 mg
Price (CNY)
2,559.00
Online Exclusive
Ends: 31-Dec-2025
3,467.00
Save 908.00 (26%)
25 mg
Add to cart

Tetramethylrhodamine, ethyl ester (TMRE) is a cell-permeant, cationic, red-orange fluorescent dye that is readily sequestered by active mitochondria.

Dissolve the dye in high-quality anhydrous DMSO or ethanol to prepare stock concentration at 1 to 10 mM.



Visualize staining your cell without wasting your reagents, antibodies, or time with our new Stain-iT Cell Staining Simulator.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Detection MethodFluorescence
Excitation/Emission549/574 nm
Molecular Weight (g/mol)514.96
Quantity25 mg
Shipping ConditionRoom Temperature
Sub Cellular LocalizationMitochondria
ColorRed-Orange
For Use With (Equipment)Fluorescence Microscope
Product TypeTMRE
Unit Size25 mg
Contents & Storage
Store in freezer (-5°C to -30°C) and protect from light.

Frequently asked questions (FAQs)

I am seeing high background outside of my neuronal cells when using membrane potential indicators. What can I do to reduce background?

If you use our FluoVolt Membrane Potential Kit (Cat. No. F10488), the kit provides a background suppressor to reduce this problem. For other indicators, consider the use of BackDrop Background Suppressor (Cat no. R37603, B10511, and B10512).

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

What is the difference between fast and slow-response membrane potential probes?

Molecules that change their structure in response to the surrounding electric field can function as fast-response probes for the detection of transient (millisecond) potential changes. Slow-response dyes function by entering depolarized cells and binding to proteins or membranes. Increased depolarization results in additional dye influx and an increase in fluorescence, while hyperpolarization is indicated by a decrease in fluorescence. Fast-response probes are commonly used to image electrical activity from intact heart tissues or measure membrane potential changes in response to pharmacological stimuli. Slow-responding probes are often used to explore mitochondrial function and cell viability.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

What type of membrane potential indicators do you offer and how should I choose one for my experiment?

A membrane potential indicator selection guide can be found here (https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cell-viability-and-regulation/ion-indicators/membrane-potential-indicators.html).

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.