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引用和文献 (5)
Thermo Scientific™
DMS（丙二酸二甲酯）
Thermo Scientific Pierce DMS 是辛二亚氨酸二甲酯二盐酸盐（一种膜可透过性交联剂），在 8 原子间隔臂各端含有胺反应性亚氨酸酯基团。辛二亚氨酸二甲酯二盐酸盐的特点：•反应性基团：亚氨酸酯了解更多信息
| 货号 | 数量 |
|---|---|
| 20700 | 1 g |
货号 20700
价格（CNY)
2,601.00
Each
数量:
1 g
价格（CNY)
2,601.00
Each
Thermo Scientific Pierce DMS 是辛二亚氨酸二甲酯二盐酸盐（一种膜可透过性交联剂），在 8 原子间隔臂各端含有胺反应性亚氨酸酯基团。
辛二亚氨酸二甲酯二盐酸盐的特点：
•反应性基团：亚氨酸酯（两端）
•可与以下基团发生反应：氨基（伯胺）
•三种类似亚氨酸酯交联剂中最长的一种，包括 DMA、DMP 和 DMS
•水溶性
•亚氨酸酯在碱性 pH 值（pH 值 8-10）下与胺反应，形成脒键
•脒键保留蛋白伯胺（反应基团）的净电荷特性
•在高 pH 值下可逆
•可用于蛋白四级结构的研究
产品参考文献
交联剂应用指南 -- 检索本产品的最新参考文献
相关产品
DMA（二甲基己二亚酰胺化物）
DMP（庚二亚氨酸二甲酯二盐酸盐）
DTBP（Wang and Richard's 试剂）
辛二亚氨酸二甲酯二盐酸盐的特点：
•反应性基团：亚氨酸酯（两端）
•可与以下基团发生反应：氨基（伯胺）
•三种类似亚氨酸酯交联剂中最长的一种，包括 DMA、DMP 和 DMS
•水溶性
•亚氨酸酯在碱性 pH 值（pH 值 8-10）下与胺反应，形成脒键
•脒键保留蛋白伯胺（反应基团）的净电荷特性
•在高 pH 值下可逆
•可用于蛋白四级结构的研究
产品参考文献
交联剂应用指南 -- 检索本产品的最新参考文献
相关产品
DMA（二甲基己二亚酰胺化物）
DMP（庚二亚氨酸二甲酯二盐酸盐）
DTBP（Wang and Richard's 试剂）
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述DMS
形式粉末
标记方法化学标记
分子量273.2
聚乙二醇化否
产品线Pierce
数量1 g
反应一部分亚氨酸酯
运输条件环境
溶解度水
间隔臂长11.0 Å
水溶性是
化学反应性胺-胺
可裂解否
交联剂类型同型双功能团试剂
产品规格标准
产品类型交联剂
间隔子中等（10 至 30 Å）
Unit SizeEach
内容与储存
接收后，请在 4°C 下干燥储存。
常见问题解答 (FAQ)
Can you provide the shelf-life for DMS (dimethyl suberimidate)?
引用和文献 (5)
引用和文献
Abstract
Discovery of lung cancer biomarkers by profiling the plasma proteome with monoclonal antibody libraries.
Journal:Mol Cell Proteomics
PubMed ID:21947365
'A challenge in the treatment of lung cancer is the lack of early diagnostics. Here, we describe the application of monoclonal antibody proteomics for discovery of a panel of biomarkers for early detection (stage I) of non-small cell lung cancer (NSCLC). We produced large monoclonal antibody libraries directed against the
The structural characterization of a prophage-encoded extracellular DNase from Streptococcus pyogenes.
Journal:Nucleic Acids Res
PubMed ID:21948797
'The pathogenic bacterium Group A Streptococcus pyogenes produces several extracellular DNases that have been shown to facilitate invasive infection by evading the human host immune system. DNases degrade the chromatin in neutrophil extracellular traps, enabling the bacterium to evade neutrophil capture. Spd1 is a type I, nonspecific ßßa/metal-dependent nuclease from
Outer membrane lipoprotein Lpp is Gram-negative bacterial cell surface receptor for cationic antimicrobial peptides.
Journal:J Biol Chem
PubMed ID:22084237
Antimicrobial peptides/proteins (AMPs) are important components of the host innate defense mechanisms. Here we demonstrate that the outer membrane lipoprotein, Lpp, of Enterobacteriaceae interacts with and promotes susceptibility to the bactericidal activities of AMPs. The oligomeric Lpp was specifically recognized by several cationic a-helical AMPs, including SMAP-29, CAP-18, and LL-37;
Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity.
Journal:J Biol Chem
PubMed ID:21636578
RNase L and RNA-dependent protein kinase (PKR) are effectors of the interferon antiviral response that share homology in their pseudokinase and protein kinase domains, respectively. Sunitinib is an orally available, ATP-competitive inhibitor of VEGF and PDGF receptors used clinically to suppress angiogenesis and tumor growth. Sunitinib also impacts IRE1, an
Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase.
Journal:J Biol Chem
PubMed ID:22383523
TWINKLE is a nucleus-encoded human mitochondrial (mt)DNA helicase. Point mutations in TWINKLE are associated with heritable neuromuscular diseases characterized by deletions in the mtDNA. To understand the biochemical basis of these diseases, it is important to define the roles of TWINKLE in mtDNA metabolism by studying its enzymatic activities. To