BMOE(双马来酰亚胺基乙烷)
BMOE(双马来酰亚胺基乙烷)
Thermo Scientific™

BMOE(双马来酰亚胺基乙烷)

Thermo Scientific Pierce BMOE 是一种短臂马来酰亚胺交联剂,用于巯基基团(例如,蛋白或肽半胱氨酸)之间的不可逆共价偶联。BMOE 的特点:•反应性基团:马来酰亚胺(两端了解更多信息
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货号数量
2232350 mg
货号 22323
价格(CNY)
3,022.00
Each
添加至购物车
数量:
50 mg
请求批量或定制报价
价格(CNY)
3,022.00
Each
添加至购物车
Thermo Scientific Pierce BMOE 是一种短臂马来酰亚胺交联剂,用于巯基基团(例如,蛋白或肽半胱氨酸)之间的不可逆共价偶联。

BMOE 的特点:

反应性基团:马来酰亚胺(两端)
可与以下基团发生反应:巯基基团
•短 (8.0Å) 的巯基-巯基交联剂,由马来酰亚胺基团和 7-原子间隔臂组成
•可用于近距离交联的最短双马来酰亚胺
• 不溶于水—首先溶于 DMF 或 DMSO 中,然后添加至水性反应缓冲液
• 不可切割

相关产品
BMB(1,4-双马来酰亚胺基丁烷)
BMH(双马来酰亚胺基己烷)
BM(PEG)2(1,8-双马来酰亚胺基-二乙二醇)
BM(PEG)3(1,11-双马来酰亚胺基-三乙二醇)
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性
描述BMOE
形式实心
标记方法化学标记
分子量220.18
聚乙二醇化
产品线Pierce
数量50 mg
反应一部分马来酰亚胺
运输条件环境
溶解度DMF、DMSO
间隔臂长8.0 Å
水溶性
化学反应性巯基-巯基
可裂解
交联剂类型同型双功能团试剂
产品规格标准
产品类型交联剂
间隔子短 (<10 Å)
Unit SizeEach
内容与储存
接收后,储存在 4°C 下。

常见问题解答 (FAQ)

Can you provide the shelf-life for BMOE (bismaleimidoethane)?

BMOE (bismaleimidoethane) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.

引用和文献 (3)

引用和文献
Abstract
Structure-based analysis of VDAC1 protein: defining oligomer contact sites.
Authors:Geula S, Naveed H, Liang J, Shoshan-Barmatz V
Journal:J Biol Chem
PubMed ID:22117062
'The outer mitochondrial membrane protein, the voltage-dependent anion channel (VDAC), is increasingly implicated in the control of apoptosis. Oligomeric assembly of VDAC1 was shown to be coupled to apoptosis induction, with oligomerization increasing substantially upon apoptosis induction and inhibited by apoptosis blockers. In this study, structure- and computation-based selection of ... More
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis.
Authors:Kida Y, Morimoto F, Sakaguchi M
Journal:J Cell Biol
PubMed ID:18166653
During protein integration into the endoplasmic reticulum, the N-terminal domain preceding the type I signal-anchor sequence is translocated through a translocon. By fusing a streptavidin-binding peptide tag to the N terminus, we created integration intermediates of multispanning membrane proteins. In a cell-free system, N-terminal domain (N-domain) translocation was arrested by ... More
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.
Authors:Auclair JR, Boggio KJ, Petsko GA, Ringe D, Agar JN
Journal:Proc Natl Acad Sci U S A
PubMed ID:21098299
Amyotrophic lateral sclerosis (ALS) is a disorder characterized by the death of both upper and lower motor neurons and by 3- to 5-yr median survival postdiagnosis. The only US Food and Drug Administration-approved drug for the treatment of ALS, Riluzole, has at best, moderate effect on patient survival and quality ... More